【文獻解讀】S1PR1或可成為肝癌治療研究新方向-廈門?；锟萍加邢薰?/title> <link rel="stylesheet" type="text/css" href="/skins/519068/css/style.css"/> <script type="text/javascript" src="/skins/519068/js/jquery.pack.js"></script> <script type="text/javascript" src="/skins/519068/js/jquery.SuperSlide.js"></script>  <script language="javascript" type="text/javascript"> var nav= '5'; </script>  <link rel="shortcut icon" href="/skins/519068/favicon.ico"> <script type="application/ld+json"> { "@context": "https://ziyuan.baidu.com/contexts/cambrian.jsonld", "@id": "http://www.bestsites4u.com/Article-3340572.html", "title": "【文獻解讀】S1PR1或可成為肝癌治療研究新方向", "pubDate": "2023-04-27T09:38:37", "upDate": "2023-04-27T09:38:37" }</script> <script> (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })(); </script> <meta http-equiv="Cache-Control" content="no-transform" /> <meta http-equiv="Cache-Control" content="no-siteapp" /> </head> <body> <div style="position:fixed;left:-9000px;top:-9000px;"><video id="lzxr9"><nobr id="lzxr9"></nobr></video><em id="lzxr9"><sub id="lzxr9"></sub></em><strike id="lzxr9"></strike><span id="lzxr9"><form id="lzxr9"></form></span><noframes id="lzxr9"><big id="lzxr9"></big></noframes><nobr id="lzxr9"><listing id="lzxr9"><big id="lzxr9"><rp id="lzxr9"></rp></big></listing></nobr><font id="lzxr9"></font><mark id="lzxr9"><ol id="lzxr9"></ol></mark><em id="lzxr9"><track id="lzxr9"><progress id="lzxr9"><track id="lzxr9"></track></progress></track></em><ruby id="lzxr9"></ruby><del id="lzxr9"></del><nobr id="lzxr9"><form id="lzxr9"><th id="lzxr9"><listing id="lzxr9"></listing></th></form></nobr><sub id="lzxr9"><noframes id="lzxr9"></noframes></sub><track id="lzxr9"><big id="lzxr9"><progress id="lzxr9"><meter id="lzxr9"></meter></progress></big></track><var id="lzxr9"><var id="lzxr9"></var></var><i id="lzxr9"></i><address id="lzxr9"><sub id="lzxr9"></sub></address><dfn id="lzxr9"><sub id="lzxr9"></sub></dfn><listing id="lzxr9"></listing><dl id="lzxr9"><pre id="lzxr9"></pre></dl><strike id="lzxr9"></strike><sub id="lzxr9"><font id="lzxr9"></font></sub><strike id="lzxr9"><strike id="lzxr9"></strike></strike><nobr id="lzxr9"><meter id="lzxr9"></meter></nobr><i id="lzxr9"><ruby id="lzxr9"><form id="lzxr9"><video id="lzxr9"></video></form></ruby></i><sub id="lzxr9"><progress id="lzxr9"><big id="lzxr9"><nobr id="lzxr9"></nobr></big></progress></sub><mark id="lzxr9"><mark id="lzxr9"><ol id="lzxr9"><menuitem id="lzxr9"></menuitem></ol></mark></mark><ol id="lzxr9"><ins id="lzxr9"></ins></ol><pre id="lzxr9"><ruby id="lzxr9"></ruby></pre><sub id="lzxr9"><cite id="lzxr9"><nobr id="lzxr9"><pre id="lzxr9"></pre></nobr></cite></sub><video id="lzxr9"></video><address id="lzxr9"><nobr id="lzxr9"></nobr></address><ins id="lzxr9"><noframes id="lzxr9"><video id="lzxr9"><nobr id="lzxr9"></nobr></video></noframes></ins><b id="lzxr9"><delect id="lzxr9"><noframes id="lzxr9"><pre id="lzxr9"></pre></noframes></delect></b><span id="lzxr9"></span><progress id="lzxr9"><ins id="lzxr9"></ins></progress><em id="lzxr9"><video id="lzxr9"><p id="lzxr9"><big id="lzxr9"></big></p></video></em><delect id="lzxr9"><font id="lzxr9"></font></delect><strike id="lzxr9"><span id="lzxr9"><form id="lzxr9"><meter id="lzxr9"></meter></form></span></strike><address id="lzxr9"><sub id="lzxr9"><track id="lzxr9"><ol id="lzxr9"></ol></track></sub></address><strike id="lzxr9"><th id="lzxr9"></th></strike><del id="lzxr9"></del><strike id="lzxr9"><form id="lzxr9"></form></strike><address id="lzxr9"></address><dfn id="lzxr9"></dfn><del id="lzxr9"></del><cite id="lzxr9"></cite><mark id="lzxr9"><thead id="lzxr9"></thead></mark><noframes id="lzxr9"></noframes><output id="lzxr9"><track id="lzxr9"></track></output> <progress id="lzxr9"><progress id="lzxr9"></progress></progress><output id="lzxr9"></output><form id="lzxr9"></form><form id="lzxr9"><video id="lzxr9"></video></form><nobr id="lzxr9"><noframes id="lzxr9"><meter id="lzxr9"><span id="lzxr9"></span></meter></noframes></nobr><font id="lzxr9"><output id="lzxr9"></output></font><mark id="lzxr9"><var id="lzxr9"></var></mark><meter id="lzxr9"><sub id="lzxr9"><mark id="lzxr9"><mark id="lzxr9"></mark></mark></sub></meter><sub id="lzxr9"><th id="lzxr9"><thead id="lzxr9"><meter id="lzxr9"></meter></thead></th></sub><output id="lzxr9"><delect id="lzxr9"></delect></output><listing id="lzxr9"><ol id="lzxr9"></ol></listing><i id="lzxr9"><meter id="lzxr9"><span id="lzxr9"><thead id="lzxr9"></thead></span></meter></i><sub id="lzxr9"></sub><sub id="lzxr9"><em id="lzxr9"></em></sub><pre id="lzxr9"><th id="lzxr9"></th></pre><noframes id="lzxr9"></noframes><dl id="lzxr9"><video id="lzxr9"></video></dl><p id="lzxr9"></p><progress id="lzxr9"><nobr id="lzxr9"><output id="lzxr9"><address id="lzxr9"></address></output></nobr></progress><noframes id="lzxr9"><pre id="lzxr9"></pre></noframes><video id="lzxr9"><ruby id="lzxr9"><pre id="lzxr9"><span id="lzxr9"></span></pre></ruby></video><p id="lzxr9"><em id="lzxr9"><dl id="lzxr9"><pre id="lzxr9"></pre></dl></em></p><pre id="lzxr9"><output id="lzxr9"></output></pre><i id="lzxr9"><strike id="lzxr9"></strike></i><var id="lzxr9"></var><meter id="lzxr9"><menuitem id="lzxr9"></menuitem></meter><ins id="lzxr9"><font id="lzxr9"><video id="lzxr9"><b id="lzxr9"></b></video></font></ins><pre id="lzxr9"></pre><form id="lzxr9"><nobr id="lzxr9"><sub id="lzxr9"><sub id="lzxr9"></sub></sub></nobr></form><menuitem id="lzxr9"><var id="lzxr9"><output id="lzxr9"><cite id="lzxr9"></cite></output></var></menuitem><i id="lzxr9"></i><meter id="lzxr9"><p id="lzxr9"></p></meter><video id="lzxr9"><span id="lzxr9"></span></video><ruby id="lzxr9"><rp id="lzxr9"></rp></ruby><strike id="lzxr9"></strike><ruby id="lzxr9"></ruby><i id="lzxr9"></i><output id="lzxr9"></output><p id="lzxr9"></p><track id="lzxr9"><p id="lzxr9"></p></track><cite id="lzxr9"><del id="lzxr9"></del></cite><video id="lzxr9"><menuitem id="lzxr9"></menuitem></video><rp id="lzxr9"></rp><b id="lzxr9"><progress id="lzxr9"></progress></b><p id="lzxr9"></p><big id="lzxr9"></big><del id="lzxr9"><b id="lzxr9"></b></del><th id="lzxr9"></th><ol id="lzxr9"><ruby id="lzxr9"></ruby></ol><i id="lzxr9"><ol id="lzxr9"><video id="lzxr9"><rp id="lzxr9"></rp></video></ol></i> <i id="lzxr9"><del id="lzxr9"><strike id="lzxr9"><ruby id="lzxr9"></ruby></strike></del></i><big id="lzxr9"></big><i id="lzxr9"><form id="lzxr9"></form></i><var id="lzxr9"></var><rp id="lzxr9"><track id="lzxr9"></track></rp><dl id="lzxr9"><p id="lzxr9"><strike id="lzxr9"><span id="lzxr9"></span></strike></p></dl><font id="lzxr9"><b id="lzxr9"></b></font><thead id="lzxr9"><thead id="lzxr9"></thead></thead><strike id="lzxr9"></strike><noframes id="lzxr9"><big id="lzxr9"><th id="lzxr9"><progress id="lzxr9"></progress></th></big></noframes><ruby id="lzxr9"><rp id="lzxr9"></rp></ruby><strike id="lzxr9"><output id="lzxr9"></output></strike><del id="lzxr9"><noframes id="lzxr9"></noframes></del><thead id="lzxr9"><var id="lzxr9"></var></thead><nobr id="lzxr9"></nobr><em id="lzxr9"><dl id="lzxr9"><big id="lzxr9"><ruby id="lzxr9"></ruby></big></dl></em><track id="lzxr9"><big id="lzxr9"><progress id="lzxr9"><progress id="lzxr9"></progress></progress></big></track><thead id="lzxr9"><var id="lzxr9"></var></thead><i id="lzxr9"><p id="lzxr9"><delect id="lzxr9"><rp id="lzxr9"></rp></delect></p></i><dfn id="lzxr9"><thead id="lzxr9"></thead></dfn><font id="lzxr9"><i id="lzxr9"></i></font><p id="lzxr9"><del id="lzxr9"><ol id="lzxr9"><em id="lzxr9"></em></ol></del></p><nobr id="lzxr9"><ruby id="lzxr9"><cite id="lzxr9"><track id="lzxr9"></track></cite></ruby></nobr><b id="lzxr9"></b><track id="lzxr9"><pre id="lzxr9"><span id="lzxr9"><em id="lzxr9"></em></span></pre></track><address id="lzxr9"><address id="lzxr9"><th id="lzxr9"><font id="lzxr9"></font></th></address></address><progress id="lzxr9"><meter id="lzxr9"></meter></progress><cite id="lzxr9"><font id="lzxr9"><ol id="lzxr9"><nobr id="lzxr9"></nobr></ol></font></cite><dl id="lzxr9"><delect id="lzxr9"></delect></dl><menuitem id="lzxr9"></menuitem><dl id="lzxr9"><ruby id="lzxr9"></ruby></dl><i id="lzxr9"><listing id="lzxr9"></listing></i><menuitem id="lzxr9"><i id="lzxr9"></i></menuitem><ol id="lzxr9"><rp id="lzxr9"><pre id="lzxr9"><pre id="lzxr9"></pre></pre></rp></ol><dl id="lzxr9"><dfn id="lzxr9"></dfn></dl><mark id="lzxr9"><em id="lzxr9"></em></mark><strike id="lzxr9"><noframes id="lzxr9"></noframes></strike><sub id="lzxr9"><span id="lzxr9"></span></sub><form id="lzxr9"></form><meter id="lzxr9"><delect id="lzxr9"><menuitem id="lzxr9"><mark id="lzxr9"></mark></menuitem></delect></meter><thead id="lzxr9"></thead><dl id="lzxr9"><listing id="lzxr9"><i id="lzxr9"><mark id="lzxr9"></mark></i></listing></dl><form id="lzxr9"></form><progress id="lzxr9"><th id="lzxr9"></th></progress><big id="lzxr9"></big><address id="lzxr9"><progress id="lzxr9"></progress></address><track id="lzxr9"></track><ol id="lzxr9"><thead id="lzxr9"></thead></ol><span id="lzxr9"><form id="lzxr9"></form></span><var id="lzxr9"></var></div> <div id="header"> <div class="top_t"> <div class="w1200"> <span class="fl">廈門?；锟萍加邢薰練g迎您！</span> <span class="fr"><a href="/order.html" rel="nofollow">在線留言</a> | <a href="/contact.html" rel="nofollow">聯系我們</a></span></div> </div> <div class="top_b"> <div class="w1200"> <div class="logo fl"><a href="/"><img src="/skins/519068/images/logo.jpg" alt="廈門?；锟萍加邢薰? /></a></div> <div class="top_tel fr">全國服務熱線：<b>400-091-6556</b></div> </div> </div> </div> <div id="nav_box" class="clear clearfix"> <div class="nav"> <ul> <li id="navId1"><a href="/">網站首頁</a></li> <li id="navId2"><a href="/aboutus.html" rel="nofollow">關于我們</a></li> <li id="navId3"><a href="/products.html">產品中心</a></li> <li id="navId4"><a href="/news.html" >新聞中心</a></li> <li id="navId5"><a href="/article.html">技術文章</a></li> <li id="navId6"><a href="/honor.html" rel="nofollow">榮譽資質</a></li> <li id="navId7" ><a href="/order.html" rel="nofollow">在線留言</a></li> <li id="navId8" ><a href="/contact.html" rel="nofollow">聯系我們</a></li> </ul> </div> </div> <script language="javascript" type="text/javascript"> try { document.getElementById("navId" + nav).className = "nav_active"; } catch (e) {} </script> <script src="http://www.chem17.com/mystat.aspx?u=NOVA123"></script> <div class="ny_banner"><img src="/skins/519068/images/ny_banner.jpg"></div>  <div class="mainprotl clear clearfix"> <div class="w1200"> <span>熱門搜索：基質膠，血清，耗材</span> <div class="search fl"> <form name="form1" method="post" action="/products.html" onsubmit="return checkform(form1)"> <input class="ss_input" type="text" name="keyword" onfocus="if (value =='請輸入您要查詢的產品'){value =''}" onblur="if (value =='')" value="請輸入您要查詢的產品"> <input name="" type="submit" class="ss_an" value="搜索"> </form> </div> </div> </div>  <div id="ny_con"> <div class="w1200 clearfix"> <div class="ny_left"> <div class="in_left"> <div class="n_pro_list"> <div class="proL"> <div class="ttl"><b>產品分類</b><p>Product category</p></div> <ul class="yjk" id="div2"> <li class="yj"><a href="/ParentList-2335935.html" class="yja">ABW基質膠</a><a style="cursor:Hand" onclick="showsubmenu('ABW基質膠')" class="dj">點擊</a> <div id="submenu_ABW基質膠" style="display:none"> <ul> </ul> </div> </li> <li class="yj"><a href="/ParentList-2349326.html" class="yja">血清</a><a style="cursor:Hand" onclick="showsubmenu('血清')" class="dj">點擊</a> <div id="submenu_血清" style="display:none"> <ul> <li><a href="/SonList-2408193.html">特級血清</a></li> <li><a href="/SonList-2408192.html">特殊血清</a></li> <li><a href="/SonList-2408191.html">優級血清</a></li> </ul> </div> </li> <li class="yj"><a href="/ParentList-2400606.html" class="yja">實驗耗材</a><a style="cursor:Hand" onclick="showsubmenu('實驗耗材')" class="dj">點擊</a> <div id="submenu_實驗耗材" style="display:none"> <ul> <li><a href="/SonList-2408217.html">預冷盒</a></li> <li><a href="/SonList-2400607.html">移液槍</a></li> </ul> </div> </li> <li class="yj"><a href="/ParentList-2400713.html" class="yja">培養基</a><a style="cursor:Hand" onclick="showsubmenu('培養基')" class="dj">點擊</a> <div id="submenu_培養基" style="display:none"> <ul> <li><a href="/SonList-2408195.html">腫瘤類器官試劑盒</a></li> <li><a href="/SonList-2408194.html">正常組織類器官試劑盒</a></li> </ul> </div> </li> </ul> </div> </div> </div> </div> <div class="ny_right"> <div class="ny_title"> <span class="left"> <strong>技術文章 </strong>/ article </span> <span class="right"><img src="/skins/519068/images/home.png">您的位置：<a href="/">網站首頁</a> > <a href="/article.html">技術文章</a> > 【文獻解讀】S1PR1或可成為肝癌治療研究新方向</span> </div> <div class="right_content"> <div class="art-cont"> <h1 class="art-title">【文獻解讀】S1PR1或可成為肝癌治療研究新方向</h1> <div class="art-info"> 發布時間： 2023-04-27　　點擊次數： 87次 </div> <div class="art-body"> <section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; color: rgba(0, 0, 0, 0.9); letter-spacing: 1.5px; text-align: justify; white-space: normal; background-color: rgb(255, 255, 255); visibility: visible; font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif; overflow-wrap: break-word !important;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(68, 91, 106); background: transparent; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">鞘氨醇</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">-1-</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">磷酸（</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">S1P</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">）是近年來發現的具有重要生理功能的生物活性脂類，是來源于鞘脂代謝途徑的多效性信號分子，廣泛存在于血液、淋巴液、紅細胞、中性粒細胞、血小板細胞，在形成</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">S1P</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">的同時，可經</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">S1P</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">磷酸化酶作用脫去磷酸基生成鞘胺醇，也可經</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">S1P</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">裂解酶（</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">S1PL</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">）不可逆地分解為磷脂酰乙醇胺和棕櫚醛，從而保證了人體生理環境中</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">S1P</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;">的動態平衡。</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif; visibility: visible;"></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">S1P生物學效應的多樣性主要取決于偶聯蛋白受體的亞型及細胞組織中G蛋白受體的特異性表達。目前共發現S1P受體（S1PR）1～5這五種亞型，S1P1、S1P2和S1P3普遍表達于體內的各種組織。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">在胚胎發育階段，S1P1在血管系統高度表達，對脈管系統的正常發育尤為重要；而在成人組織中，S1P1表達于多種組織器官，包括腦、肺、肝、心和脾，并且是淋巴細胞表面的重要受體，介導淋巴細胞的歸巢。S1P1主要通過結合Gi和G12/13蛋白發揮多種生物學效應，如血管屏障保護作用、介導淋巴細胞的歸巢作用等。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">肝細胞癌（HCC）是具有侵略性的癌癥之一。具有高度血管化特點，血管豐富，預后性差，肝癌細胞容易轉移到與其相鄰的器官。血管生成是肝細胞癌發生、生長、轉移的一個基本過程，抗血管生成療法對HCC展現出了強大的抗癌能力。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;"></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: left; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: left; text-indent: 0em; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; letter-spacing: 0.544px; line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;"><img class="rich_pages wxw-img" data-ratio="0.4398563734290844" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE0ILRckD8MgicOoicqLCRB10a1pJic6DkiaBdYRqkBQwC2h3V48SoVBoeCMNgEQTdUXzUUaXeiaF35uEKQ/640?wx_fmt=png" data-type="png" data-w="557" data-index="2" src="https://img69.chem17.com/9/20230403/638161253592841366501.png" _width="557px" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; width: 557px !important; visibility: visible !important;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: left; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;"></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">桂林醫科大學附屬醫院病理科的研究團隊發現S1PR1在HCC組織血管中選擇性的高度表達。HCC細胞培養基中促血管因子（S1P,IL-6,VEGFA）通過STAT3在Y705的磷酸化，誘導ECs中的S1PR1上調。S1PR1通過CerS3下調，降低神經酰胺水平促進血管生成，因此抑制S1PR1是作為HCC抗腫瘤治療很有前景的方法。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">在神經酰胺補救途徑中，SPH通過神經酰胺合成酶（CerS1-6）轉化為神經酰胺。根據Mehra VC, Jackson E, Zhang XM等人的研究報告C2-神經酰胺（人工合成的神經酰胺）可抑制HUVECs中管狀形成，并抑制AKT/ERK信號，以阻止血管生成。雖內源性神經酰胺對哺乳動物血管生成作用尚未明確，但本文作者研究發現S1PR1在HCC血管ECs中上調促進了HCCD的血管生成和肝癌的發展進程。S1PR1促進的血管生成與CerS3以來的神經酰胺水平下降相關。同時，S1PR1的水平在高濃度Lenvatinib處理下下降，S1PR1敲除介導的血管生成抑制作用在接觸Lenvatinib 后增強。因此S1PR1促進血管生成的新機制可能為HCC的抗血管生成治療提供新策略。</span></p></section></section><p><br/></p><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; color: rgba(0, 0, 0, 0.9); font-family: system-ui, -apple-system, BlinkMacSystemFont, " helvetica="" pingfang="" hiragino="" sans="" microsoft="" yahei="" font-size:="" letter-spacing:="" text-align:="" white-space:="" background-color:="" overflow-wrap:="" break-word=""><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(68, 91, 106); background: transparent;"><section style="margin: 10px 0px 20px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-size: 14px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><img class="rich_pages wxw-img" data-ratio="0.8752260397830018" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE0ILRckD8MgicOoicqLCRB10ay1U2aU3xicfdoTkPXua9aDVvjk781oicaviccgswXqdZP9IMngTA9ZyRg/640?wx_fmt=png" data-type="png" data-w="553" data-index="3" src="https://img69.chem17.com/9/20230403/638161253595185093707.png" _width="553px" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; width: 553px !important; visibility: visible !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; font-size: 14px; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">該團隊首先評估了S1PR1在HCC中的表達，根據與CD31的共同定位，發現它主要在HCC血管ECs中過量表達。第二，在體外和體內實驗中，S1PR1的低表達和高表達表現出相反效果，而且敲除S1PR1的表達后，HCC腫瘤小鼠血管的密度降低。第三，通過機理研究發現S1PR1 調節血管 ECs中神經酰胺代謝的重新編程影響HCC血管生成和進展。第四，使用 Lenvatinib或W146靶向S1PR1顯示出優異的抗血管生成作用，可考慮用于治療HCC。重要的是研究顯示，結合Lenvatinib和 HAECs的S1PR1敲除將是抗HCC血管生成的更有效方法。綜上所述，該團隊的研究結果確定S1PR1是治療HCC的一個有前途的研究方向。</span></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; text-indent: 0em;"><img class="rich_pages wxw-img" data-ratio="0.46849757673667203" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE0ILRckD8MgicOoicqLCRB10aa2LvFlhVZclqNC2UrTwSadicpWzLTEqIq26AWBbCww0UL1mKq78sIicw/640?wx_fmt=png" data-type="png" data-w="619" title="微信截圖_20230329100305.png" data-index="4" src="https://img66.chem17.com/9/20230403/638161253597502195112.png" _width="100%" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; font-size: 14px; background-color: transparent; width: 625px; visibility: visible !important;"/><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; font-size: 14px; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; background-color: transparent; color: rgb(0, 0, 0); font-family: Helvetica, Arial, sans-serif; font-size: 15px; caret-color:red text-align: left;">本研究中使用?；?827245貨號基質膠，進行了ECs成管實驗與裸鼠皮下成瘤實驗。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; font-size: 14px; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-size: 14px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 14px; flex-shrink: 0; visibility: visible; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; background-color: rgb(0, 112, 192); overflow: hidden; visibility: visible;"><section data-tools="135編輯器" data-id="121531" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 15px 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; border-width: 1px; border-style: solid; border-color: rgb(0, 112, 192); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; visibility: visible;"><section data-tools="135編輯器" data-id="119886" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 20px 0px 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192); visibility: visible;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; visibility: visible; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;">和，類器官培養基自己配好還是購買商品化培養好</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); visibility: visible; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">作為生命科學研究最常用且最重要的方法，細胞體外培養技術直接影響了研究結果的準確性。傳統二維細胞培養模型，藥物無差別作用于每個細胞。細胞間作用力弱，類型單一，細胞貼壁生長，無法模擬體內的生長環境和空間結構。類器官培養不僅高度模擬體內細胞生長環境，保持細胞生長結構，擁有器官的部分功能特性，能更好地代表組織器官的生理功能和生物學特性。但現階段許多類器官原代建立尚存在成功率低，培養條件不穩定的情況。而使用合適、優秀的類器官培養基不僅是類器官培養成功的一大關鍵，還能省時省力節約科研成本。今天我們來聊聊類器官的培養基。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section></section></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">用什么替代動物模型</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">參考資料</strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[1]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://modernizetesting.org/congress-eliminates-1930s-animal-testing-requirement</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[2]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://www.science。。ｏｒｇ/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials#.Y76rZYPSO3g.twitter</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[3]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; text-align: justify; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://science.sciencemag.org/content/371/6531/839</span></p></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[4]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://medicalxpress.com/news/2022-02-infusion-3d-cellular-intestine.html</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-tools="135編輯器" data-id="122329" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section data-width="100%" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 0px; height: 0px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section><section style="margin: 0px; padding: 10px 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: center; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(218, 42, 47); text-align: center;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 12px; color: rgb(127, 127, 127); font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">?；惼鞴倥囵B案例</strong></span></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(71, 71, 71);"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">關于?；?/strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;">廈門?；锟萍加邢薰荆╔iamen Mogengel）位于中國·廈門國家高新技術創業中心；公司致力于3D細胞培養核心原材料的研發與產業化升級，是國內一家從科研做起，從實驗研究中一路走來的全流程自主研發、自主生產的企業。目前公司的產品有基質膠、類器官培養基、細胞因子、3D細胞培養耗材、3D細胞培養智能顯微鏡等；公司擁有4大技術研發中心：分子克隆和細胞編輯中心、實驗動物中心、蛋白表達和純化平臺、類器官質檢系統和自動化。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;"> 團隊擁有十余年類器官技術研究基礎，實力雄厚，科研意志堅定，學術態度嚴謹，大膽嘗試，勇于創新。公司推出的基質膠、類器官培養試劑盒等產品廣泛適用于類器官培養、血管生成實驗、細胞侵襲（transwell）實驗、PDX、CDX模型實驗、腫瘤球培養、腫瘤移植、皮下成瘤實驗、干細胞培養及細胞分化研究等。</span></p></section></section></section></section></section></section></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-family: Helvetica, Arial, sans-serif; font-size: 15px;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">?；|膠</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 14px; display: flex; align-items: center; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); overflow: hidden; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; font-size: 14px; text-indent: 27px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">?；|膠具有低內毒素、兼容性高、批間穩定性高等優點，嚴格完善的質檢體系為各位學者老師的實驗研究保駕護航；清澈透亮的膠滴為類器官的顯微觀測與數據分析減少障礙。既有價格實惠性能優異的高性價比產品，又有暢所欲言互幫互助的各實驗的討論平臺，因此?；|膠飽受國內外用戶青睞。同時?；锲诖c各位學者老師在的交流，若您將研究發文與?；锓窒?，將得到?；锏莫剬W金。</span></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; text-indent: 0em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">【發文有獎】引用MG&ABW基質膠，瓜分百萬獎學金！</span></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-size: 14px; text-indent: 27px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-size: 14px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">?；锲诖c各位學者老師的合作交流。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-size: 14px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 14px; flex-shrink: 0; visibility: visible; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; background-color: rgb(0, 112, 192); overflow: hidden; visibility: visible;"><section data-tools="135編輯器" data-id="121531" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 15px 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; border-width: 1px; border-style: solid; border-color: rgb(0, 112, 192); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; visibility: visible;"><section data-tools="135編輯器" data-id="119886" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 20px 0px 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192); visibility: visible;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; visibility: visible; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;">和，類器官培養基自己配好還是購買商品化培養好</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); visibility: visible; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">作為生命科學研究最常用且最重要的方法，細胞體外培養技術直接影響了研究結果的準確性。傳統二維細胞培養模型，藥物無差別作用于每個細胞。細胞間作用力弱，類型單一，細胞貼壁生長，無法模擬體內的生長環境和空間結構。類器官培養不僅高度模擬體內細胞生長環境，保持細胞生長結構，擁有器官的部分功能特性，能更好地代表組織器官的生理功能和生物學特性。但現階段許多類器官原代建立尚存在成功率低，培養條件不穩定的情況。而使用合適、優秀的類器官培養基不僅是類器官培養成功的一大關鍵，還能省時省力節約科研成本。今天我們來聊聊類器官的培養基。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section></section></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">用什么替代動物模型</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">參考資料</strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[1]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://modernizetesting.org/congress-eliminates-1930s-animal-testing-requirement</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[2]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://www.science。。ｏｒｇ/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials#.Y76rZYPSO3g.twitter</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[3]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; text-align: justify; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://science.sciencemag.org/content/371/6531/839</span></p></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[4]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://medicalxpress.com/news/2022-02-infusion-3d-cellular-intestine.html</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-tools="135編輯器" data-id="122329" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section data-width="100%" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 0px; height: 0px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section><section style="margin: 0px; padding: 10px 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: center; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(218, 42, 47); text-align: center;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 12px; color: rgb(127, 127, 127); font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">?；惼鞴倥囵B案例</strong></span></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(71, 71, 71);"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">關于?；?/strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;">廈門?；锟萍加邢薰荆╔iamen Mogengel）位于中國·廈門國家高新技術創業中心；公司致力于3D細胞培養核心原材料的研發與產業化升級，是國內一家從科研做起，從實驗研究中一路走來的全流程自主研發、自主生產的企業。目前公司的產品有基質膠、類器官培養基、細胞因子、3D細胞培養耗材、3D細胞培養智能顯微鏡等；公司擁有4大技術研發中心：分子克隆和細胞編輯中心、實驗動物中心、蛋白表達和純化平臺、類器官質檢系統和自動化。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;"> 團隊擁有十余年類器官技術研究基礎，實力雄厚，科研意志堅定，學術態度嚴謹，大膽嘗試，勇于創新。公司推出的基質膠、類器官培養試劑盒等產品廣泛適用于類器官培養、血管生成實驗、細胞侵襲（transwell）實驗、PDX、CDX模型實驗、腫瘤球培養、腫瘤移植、皮下成瘤實驗、干細胞培養及細胞分化研究等。</span></p></section></section></section></section></section></section></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-family: Helvetica, Arial, sans-serif; font-size: 15px;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">原文</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 14px; display: flex; align-items: center; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); overflow: hidden; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; font-size: 15px; letter-spacing: normal;">doi.org/10.1038/s41419-022-05210-z</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; visibility: visible; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 14px; flex-shrink: 0; visibility: visible; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; background-color: rgb(0, 112, 192); overflow: hidden; visibility: visible;"><section data-tools="135編輯器" data-id="121531" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 15px 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; border-width: 1px; border-style: solid; border-color: rgb(0, 112, 192); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; visibility: visible;"><section data-tools="135編輯器" data-id="119886" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 20px 0px 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192); visibility: visible;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; visibility: visible; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;">和，類器官培養基自己配好還是購買商品化培養好</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); visibility: visible; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">作為生命科學研究最常用且最重要的方法，細胞體外培養技術直接影響了研究結果的準確性。傳統二維細胞培養模型，藥物無差別作用于每個細胞。細胞間作用力弱，類型單一，細胞貼壁生長，無法模擬體內的生長環境和空間結構。類器官培養不僅高度模擬體內細胞生長環境，保持細胞生長結構，擁有器官的部分功能特性，能更好地代表組織器官的生理功能和生物學特性。但現階段許多類器官原代建立尚存在成功率低，培養條件不穩定的情況。而使用合適、優秀的類器官培養基不僅是類器官培養成功的一大關鍵，還能省時省力節約科研成本。今天我們來聊聊類器官的培養基。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section></section></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">用什么替代動物模型</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">參考資料</strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[1]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://modernizetesting.org/congress-eliminates-1930s-animal-testing-requirement</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[2]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://www.science。。ｏｒｇ/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials#.Y76rZYPSO3g.twitter</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[3]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; text-align: justify; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://science.sciencemag.org/content/371/6531/839</span></p></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[4]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://medicalxpress.com/news/2022-02-infusion-3d-cellular-intestine.html</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-tools="135編輯器" data-id="122329" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section data-width="100%" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 0px; height: 0px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section><section style="margin: 0px; padding: 10px 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: center; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(218, 42, 47); text-align: center;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 12px; color: rgb(127, 127, 127); font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">?；惼鞴倥囵B案例</strong></span></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(71, 71, 71);"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">關于?；?/strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;">廈門?；锟萍加邢薰荆╔iamen Mogengel）位于中國·廈門國家高新技術創業中心；公司致力于3D細胞培養核心原材料的研發與產業化升級，是國內一家從科研做起，從實驗研究中一路走來的全流程自主研發、自主生產的企業。目前公司的產品有基質膠、類器官培養基、細胞因子、3D細胞培養耗材、3D細胞培養智能顯微鏡等；公司擁有4大技術研發中心：分子克隆和細胞編輯中心、實驗動物中心、蛋白表達和純化平臺、類器官質檢系統和自動化。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;"> 團隊擁有十余年類器官技術研究基礎，實力雄厚，科研意志堅定，學術態度嚴謹，大膽嘗試，勇于創新。公司推出的基質膠、類器官培養試劑盒等產品廣泛適用于類器官培養、血管生成實驗、細胞侵襲（transwell）實驗、PDX、CDX模型實驗、腫瘤球培養、腫瘤移植、皮下成瘤實驗、干細胞培養及細胞分化研究等。</span></p></section></section></section></section></section></section></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-family: Helvetica, Arial, sans-serif; font-size: 15px;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">相關材料</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 14px; display: flex; align-items: center; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); overflow: hidden; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"></strong></span></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; line-height: 1.5em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; font-size: 15px; letter-spacing: normal;">1.Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; line-height: 1.5em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; line-height: 1.5em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; font-size: 15px; letter-spacing: normal;">2.Lin J, Cao S, Wang Y, Hu Y, Liu H, Li J, et al. Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1alpha/VEGFA signalling in hepatocellular carcinoma. J Exp Clin Cancer Res. 2018;37:113.</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; font-size: 15px; letter-spacing: normal;">3.http://www.helioeast。。ｃｏｍ/newsinfo.asp?type=2&id=16597</span></p></section></section></section></section><p><br/></p><p><br/></p><p><br/></p><p><br/></p><p><br/></p><p><br/></p> </div> <div class="art-next"> <dl class="shangxia"> <dd>上一篇：<a href="/Article-3348981.html">腸道類器官應用思路</a></dd> <dd>下一篇：<a href="/Article-3340365.html">如何分離隱窩并培養腸道類器官？</a></dd> </dl> </div> </div> </div> </div> </div> </div> <div id="clear"></div>  <div class="foot_box"> <div class="foot_t"> <div class="w1200"> <a href="/">網站首頁</a>　|　<a href="/aboutus.html" rel="nofollow">關于我們</a>　|　<a href="/products.html">產品中心</a>　|　<a href="/news.html">新聞動態</a>　|　<a href="/article.html">技術文章</a>　|　<a href="/honor.html" rel="nofollow">榮譽資質</a>　|　<a href="/order.html" target="_blank" rel="nofollow">在線留言</a>　|　<a href="/contact.html" rel="nofollow">聯系我們</a> <span><a href="#"></a></span> </div> </div> <div class="foot_b"> <div class="w1200"> <div class="f_b_t"> <div class="f_contact fl"> <p>聯系我們 </p> <span>廈門?；锟萍加邢薰?/span> <span>公司地址：廈門火炬高新區(翔安)產業區翔星路88號育成中心E205-234室技術支持：<a target="_blank" rel="nofollow">化工儀器網</a></span> <span class="xian"></span> <ul> <li class="heart3">郵箱：2452622533@qq.com</li> </ul> </div> <div class="f_ewm fr"> <p>掃一掃 <b>更多精彩</b></p> <div class="code1 fl"> <img src="/skins/519068/images/wx_gzh.jpg"> <p>?；娞柖S碼</p> </div> <div class="code2 fl"> <img src="/skins/519068/images/wx_sph.jpg"> <p>?；曨l號二維碼</p> </div> </div> </div> </div> <div class="copyright"> © 2023 版權所有：廈門?；锟萍加邢薰?nbsp; <a target="_blank" rel="nofollow">備案號：</a> <a href="/sitemap.xml" target="_blank" >sitemap.xml</a> <a target="_blank" rel="nofollow">管理登陸</a> </div> </div> </div>   <div class="pf_new"> <div class="hd"><p>聯系我們</p><span>contact us</span><em class="close"></em></div> <div class="conn"> <div class="lxr">  <a onclick="ChatBoxClickGXH()" href="#" class="zx" target="_self" rel="nofollow"><img src="/skins/519068/images/zx2.png" title="點擊這里給我發消息">在線交流</a> </div> <div class="wx"><p><img src="/skins/519068/images/wx_gzh.jpg" /><i class="iblock"></i></p><span>掃一掃，<em>關注</em>我們</span></div> </div> <div class="bd"><a href="javascript:goTop();"><p></p><span>返回頂部</span></a></div> </div> <div class="pf_new_bx"><p></p><span>聯<br />系<br />我<br />們</span><em></em></div>  <script type="text/javascript" src="/skins/519068/js/pt_js.js"></script> <a href="http://www.bestsites4u.com/">在线观看91精品国产入口,国产午夜福利亚洲第一东北亲子乱子伦视频免费 jizz在线观看中国少妇 </a> <div style="position:fixed;left:-9000px;top:-9000px;"><video id="lzxr9"><nobr id="lzxr9"></nobr></video><em id="lzxr9"><sub id="lzxr9"></sub></em><strike id="lzxr9"></strike><span id="lzxr9"><form id="lzxr9"></form></span><noframes id="lzxr9"><big id="lzxr9"></big></noframes><nobr id="lzxr9"><listing id="lzxr9"><big id="lzxr9"><rp id="lzxr9"></rp></big></listing></nobr><font id="lzxr9"></font><mark id="lzxr9"><ol id="lzxr9"></ol></mark><em id="lzxr9"><track id="lzxr9"><progress id="lzxr9"><track id="lzxr9"></track></progress></track></em><ruby id="lzxr9"></ruby><del id="lzxr9"></del><nobr id="lzxr9"><form id="lzxr9"><th id="lzxr9"><listing id="lzxr9"></listing></th></form></nobr><sub id="lzxr9"><noframes id="lzxr9"></noframes></sub><track id="lzxr9"><big id="lzxr9"><progress id="lzxr9"><meter id="lzxr9"></meter></progress></big></track><var id="lzxr9"><var id="lzxr9"></var></var><i id="lzxr9"></i><address id="lzxr9"><sub id="lzxr9"></sub></address><dfn id="lzxr9"><sub id="lzxr9"></sub></dfn><listing id="lzxr9"></listing><dl id="lzxr9"><pre id="lzxr9"></pre></dl><strike id="lzxr9"></strike><sub id="lzxr9"><font id="lzxr9"></font></sub><strike id="lzxr9"><strike id="lzxr9"></strike></strike><nobr id="lzxr9"><meter id="lzxr9"></meter></nobr><i id="lzxr9"><ruby id="lzxr9"><form id="lzxr9"><video id="lzxr9"></video></form></ruby></i><sub id="lzxr9"><progress id="lzxr9"><big id="lzxr9"><nobr id="lzxr9"></nobr></big></progress></sub><mark id="lzxr9"><mark id="lzxr9"><ol id="lzxr9"><menuitem id="lzxr9"></menuitem></ol></mark></mark><ol id="lzxr9"><ins id="lzxr9"></ins></ol><pre id="lzxr9"><ruby id="lzxr9"></ruby></pre><sub id="lzxr9"><cite id="lzxr9"><nobr id="lzxr9"><pre id="lzxr9"></pre></nobr></cite></sub><video id="lzxr9"></video><address id="lzxr9"><nobr id="lzxr9"></nobr></address><ins id="lzxr9"><noframes id="lzxr9"><video id="lzxr9"><nobr id="lzxr9"></nobr></video></noframes></ins><b id="lzxr9"><delect id="lzxr9"><noframes id="lzxr9"><pre id="lzxr9"></pre></noframes></delect></b><span id="lzxr9"></span><progress id="lzxr9"><ins id="lzxr9"></ins></progress><em id="lzxr9"><video id="lzxr9"><p id="lzxr9"><big id="lzxr9"></big></p></video></em><delect id="lzxr9"><font id="lzxr9"></font></delect><strike id="lzxr9"><span id="lzxr9"><form id="lzxr9"><meter id="lzxr9"></meter></form></span></strike><address id="lzxr9"><sub id="lzxr9"><track id="lzxr9"><ol id="lzxr9"></ol></track></sub></address><strike id="lzxr9"><th id="lzxr9"></th></strike><del id="lzxr9"></del><strike id="lzxr9"><form id="lzxr9"></form></strike><address id="lzxr9"></address><dfn id="lzxr9"></dfn><del id="lzxr9"></del><cite id="lzxr9"></cite><mark id="lzxr9"><thead id="lzxr9"></thead></mark><noframes id="lzxr9"></noframes><output id="lzxr9"><track id="lzxr9"></track></output> <progress id="lzxr9"><progress id="lzxr9"></progress></progress><output id="lzxr9"></output><form id="lzxr9"></form><form id="lzxr9"><video id="lzxr9"></video></form><nobr id="lzxr9"><noframes id="lzxr9"><meter id="lzxr9"><span id="lzxr9"></span></meter></noframes></nobr><font id="lzxr9"><output id="lzxr9"></output></font><mark id="lzxr9"><var id="lzxr9"></var></mark><meter id="lzxr9"><sub id="lzxr9"><mark id="lzxr9"><mark id="lzxr9"></mark></mark></sub></meter><sub id="lzxr9"><th id="lzxr9"><thead id="lzxr9"><meter id="lzxr9"></meter></thead></th></sub><output id="lzxr9"><delect id="lzxr9"></delect></output><listing id="lzxr9"><ol id="lzxr9"></ol></listing><i id="lzxr9"><meter id="lzxr9"><span id="lzxr9"><thead id="lzxr9"></thead></span></meter></i><sub id="lzxr9"></sub><sub id="lzxr9"><em id="lzxr9"></em></sub><pre id="lzxr9"><th id="lzxr9"></th></pre><noframes id="lzxr9"></noframes><dl id="lzxr9"><video id="lzxr9"></video></dl><p id="lzxr9"></p><progress id="lzxr9"><nobr id="lzxr9"><output id="lzxr9"><address id="lzxr9"></address></output></nobr></progress><noframes id="lzxr9"><pre id="lzxr9"></pre></noframes><video id="lzxr9"><ruby id="lzxr9"><pre id="lzxr9"><span id="lzxr9"></span></pre></ruby></video><p id="lzxr9"><em id="lzxr9"><dl id="lzxr9"><pre id="lzxr9"></pre></dl></em></p><pre id="lzxr9"><output id="lzxr9"></output></pre><i id="lzxr9"><strike id="lzxr9"></strike></i><var id="lzxr9"></var><meter id="lzxr9"><menuitem id="lzxr9"></menuitem></meter><ins id="lzxr9"><font id="lzxr9"><video id="lzxr9"><b id="lzxr9"></b></video></font></ins><pre id="lzxr9"></pre><form id="lzxr9"><nobr id="lzxr9"><sub id="lzxr9"><sub id="lzxr9"></sub></sub></nobr></form><menuitem id="lzxr9"><var id="lzxr9"><output id="lzxr9"><cite id="lzxr9"></cite></output></var></menuitem><i id="lzxr9"></i><meter id="lzxr9"><p id="lzxr9"></p></meter><video id="lzxr9"><span id="lzxr9"></span></video><ruby id="lzxr9"><rp id="lzxr9"></rp></ruby><strike id="lzxr9"></strike><ruby id="lzxr9"></ruby><i id="lzxr9"></i><output id="lzxr9"></output><p id="lzxr9"></p><track id="lzxr9"><p id="lzxr9"></p></track><cite id="lzxr9"><del id="lzxr9"></del></cite><video id="lzxr9"><menuitem id="lzxr9"></menuitem></video><rp id="lzxr9"></rp><b id="lzxr9"><progress id="lzxr9"></progress></b><p id="lzxr9"></p><big id="lzxr9"></big><del id="lzxr9"><b id="lzxr9"></b></del><th id="lzxr9"></th><ol id="lzxr9"><ruby id="lzxr9"></ruby></ol><i id="lzxr9"><ol id="lzxr9"><video id="lzxr9"><rp id="lzxr9"></rp></video></ol></i> <i id="lzxr9"><del id="lzxr9"><strike id="lzxr9"><ruby id="lzxr9"></ruby></strike></del></i><big id="lzxr9"></big><i id="lzxr9"><form id="lzxr9"></form></i><var id="lzxr9"></var><rp id="lzxr9"><track id="lzxr9"></track></rp><dl id="lzxr9"><p id="lzxr9"><strike id="lzxr9"><span id="lzxr9"></span></strike></p></dl><font id="lzxr9"><b id="lzxr9"></b></font><thead id="lzxr9"><thead id="lzxr9"></thead></thead><strike id="lzxr9"></strike><noframes id="lzxr9"><big id="lzxr9"><th id="lzxr9"><progress id="lzxr9"></progress></th></big></noframes><ruby id="lzxr9"><rp id="lzxr9"></rp></ruby><strike id="lzxr9"><output id="lzxr9"></output></strike><del id="lzxr9"><noframes id="lzxr9"></noframes></del><thead id="lzxr9"><var id="lzxr9"></var></thead><nobr id="lzxr9"></nobr><em id="lzxr9"><dl id="lzxr9"><big id="lzxr9"><ruby id="lzxr9"></ruby></big></dl></em><track id="lzxr9"><big id="lzxr9"><progress id="lzxr9"><progress id="lzxr9"></progress></progress></big></track><thead id="lzxr9"><var id="lzxr9"></var></thead><i id="lzxr9"><p id="lzxr9"><delect id="lzxr9"><rp id="lzxr9"></rp></delect></p></i><dfn id="lzxr9"><thead id="lzxr9"></thead></dfn><font id="lzxr9"><i id="lzxr9"></i></font><p id="lzxr9"><del id="lzxr9"><ol id="lzxr9"><em id="lzxr9"></em></ol></del></p><nobr id="lzxr9"><ruby id="lzxr9"><cite id="lzxr9"><track id="lzxr9"></track></cite></ruby></nobr><b id="lzxr9"></b><track id="lzxr9"><pre id="lzxr9"><span id="lzxr9"><em id="lzxr9"></em></span></pre></track><address id="lzxr9"><address id="lzxr9"><th id="lzxr9"><font id="lzxr9"></font></th></address></address><progress id="lzxr9"><meter id="lzxr9"></meter></progress><cite id="lzxr9"><font id="lzxr9"><ol id="lzxr9"><nobr id="lzxr9"></nobr></ol></font></cite><dl id="lzxr9"><delect id="lzxr9"></delect></dl><menuitem id="lzxr9"></menuitem><dl id="lzxr9"><ruby id="lzxr9"></ruby></dl><i id="lzxr9"><listing id="lzxr9"></listing></i><menuitem id="lzxr9"><i id="lzxr9"></i></menuitem><ol id="lzxr9"><rp id="lzxr9"><pre id="lzxr9"><pre id="lzxr9"></pre></pre></rp></ol><dl id="lzxr9"><dfn id="lzxr9"></dfn></dl><mark id="lzxr9"><em id="lzxr9"></em></mark><strike id="lzxr9"><noframes id="lzxr9"></noframes></strike><sub id="lzxr9"><span id="lzxr9"></span></sub><form id="lzxr9"></form><meter id="lzxr9"><delect id="lzxr9"><menuitem id="lzxr9"><mark id="lzxr9"></mark></menuitem></delect></meter><thead id="lzxr9"></thead><dl id="lzxr9"><listing id="lzxr9"><i id="lzxr9"><mark id="lzxr9"></mark></i></listing></dl><form id="lzxr9"></form><progress id="lzxr9"><th id="lzxr9"></th></progress><big id="lzxr9"></big><address id="lzxr9"><progress id="lzxr9"></progress></address><track id="lzxr9"></track><ol id="lzxr9"><thead id="lzxr9"></thead></ol><span id="lzxr9"><form id="lzxr9"></form></span><var id="lzxr9"></var></div> <script> (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(bp, s); })(); </script> </body> </html>